Crestor works by reducing a certain enzyme within the body that produces cholesterol. It belongs to a class of medications called statins.
Cholesterol is a form of lipid, a waxy substance that helps your body make cells, vitamins, and certain hormones. It is not inherently bad. Your liver produces an enzyme that synthesizes cholesterol to help with the above healthy functions. Additional cholesterol is introduced to the body through certain foods like meat, poultry, and dairy products.
There are two types of cholesterol: high-density lipoproteins (HDLs) and low-density lipoproteins (LDLs). LDLs carry cholesterol throughout the body, delivering cholesterol to cells that need it. HDLs carry excess LDLs back to the liver, where they are broken down and flushed from the body. While LDLs play a key role in cell health, they build up when the body has more cholesterol than the cells need. This buildup turns into plaque in the arteries (blood vessels). As plaque covers the artery walls, the blood vessels become narrow. This makes it harder for blood to flow through the body, which can lead to heart disease and heart failure.
Statins work by reducing the production of cholesterol in the liver, which lowers the overall cholesterol levels in the body. Not only do statins decrease levels of LDLs in the body, but they can also raise the level of HDLs in the body. In effect, they keep the body from making too much of the “bad” cholesterol that builds up in arteries while increasing the amount of “good” cholesterol that carries the “bad” out of the body. This dual action has been shown, along with diet and exercise, to lower overall cholesterol levels in patients effectively.
Crestor (rosuvastatin) is an oral treatment that contains a generic brand name of sildenafil (the same drug used in other cholesterol-lowering medications), valsartan (angiotensin converting-vasoactive drugs), and lisinopril (an oral angina medication). It was FDA-approved in 1997 and has been in clinical use for more than 10 years. In clinical trials, patients taking Crestor lost about 3 pounds in just 2 weeks. Like other medications, Crestor can cause side effects such as headache, indigestion, stuffy nose, and muscle pain. These side effects are usually mild and do not need medical attention. However, Crestor is not recommended for severe side effects such as heart attack or stroke. In rare cases, Crestor can cause more serious side effects including, but are not limited to: hearing loss (ringing in the ears), kidney problems ( enlarged tubules in the urine), liver problems (nausea and vomiting), pancreatitis ( enlargement of the painful, swollen pancreas), prostate cancer ( growths in the part of the penis), or prostate cancer ( growths in the prostate). If you experience any of these side effects, stop and get medical help right away. Sudden blindness, kidney damage, and prolonged use of oral medications can be life threatening. It is not suitable for everyone. If you are pregnant or breastfeeding, talk to your doctor immediately. Crestor is not recommended for children under 18 years of age or those with liver or kidney disease. Crestor can cause liver problems and kidney problems. Discuss the risks and benefits in more detail in the manufacturer's Patient Information Leaflet (PIL) associated with the medication.Precautions (1 year) Crestor is not recommended for use in people with liver or kidney problems. In vitro studies have shown that Crestor can raise LDL levels in the blood. In vitro Crestor can also cause side effects such as kidney problems ( enlarged urine bladder), headaches, indigestion, stuffy nose, muscle pain, and kidney problems ( enlarged urinary bladder). Sudden side effects such as kidney problems ( enlarged urinary bladder) and indigestion ( difficult to empty the bladder) have been documented in some patients taking Crestor. Tell your doctor if you are taking any of the following medications: aminofloxacin, erythromycin, cisapride, cisapride lactose, cisapride ranitidine, methotrexate, medications for high blood pressure, medications for indigestion, protease inhibitors including rilpivirine, and spronoxidine. Tell your doctor if you are pregnant or plan to become pregnant. Crestor can cause liver problems. Discuss the risks and benefits with your doctor. Crestor is not recommended for use by children under 18 years of age or those with kidney problems.Roche's pharmaceutical giantoche-Zyvay Pharmaceuticals has launched the first generic version of its cholesterol-reducing drug Crestor, following the approval of its second-generation drug, Lipitor.
Lipitor is the first generic version of Lipitor, the world's top-selling drug for the treatment of atherosclerosis. Lipitor is the first statin to become available and has become one of the world's leading options for treating patients with high cholesterol.
The new generic version of Lipitor comes from a company-sponsored study that showed the drug led to a lower risk of heart attack, stroke and death in patients taking statins compared to those who took only those medicines.
Zyvay was the first to announce its decision to sell its generic Lipitor, the first statin drug to treat the symptoms of atherosclerosis.
Lipitor is a cholesterol-lowering medication that works by blocking the production of bad cholesterol. Lipitor has been available since its introduction in the 1950s to help people with cholesterol-related problems.
The drug is currently approved for use in the United States and other developed and developing countries, including the European Union and the United Kingdom, as well as the world.
Zyvay is the first company-sponsored study to link statins to a higher risk of heart attack, stroke and death in patients taking the medication. It found that patients taking Lipitor were more likely to be at a greater risk of death when compared to patients who did not take the medicine.
The new generic Lipitor was also the first to show a decrease in the risk of heart attack, stroke and death in patients taking statins compared to those taking only those medicines. The findings were published today in the European Journal of Cardiology.
"We believe this drug should be considered as a first-line treatment for patients with high cholesterol," says Dr. H. Andrew Goldstein, professor of clinical pharmacology, at the Albert Einstein College of Medicine and the University of Texas Southwestern Medical Center in Dallas. "Patients who take statins and those who take Lipitor, who are at greater risk of heart attack, stroke and death, should be closely monitored."
The study found that patients taking Lipitor were more likely to be at a greater risk of death when compared to patients who took only those medicines.Lipitor has also been shown to be effective in patients with high cholesterol who have not been taking statins. The company's study showed that patients taking Lipitor had a lower risk of cardiovascular events in comparison to patients who did not take the statins.
Dr. / Institute for Clinical Excellence
A study published today in the European Journal of Cardiology found that the combination of a statin and cholesterol lowering drug led to an increase in the risk of a heart attack or stroke in patients taking Lipitor compared to patients taking only statins.Lipitor was originally developed to help patients who are at a greater risk of developing high cholesterol. It has been used in patients with high cholesterol to help them manage their cholesterol problems.The study found that patients taking Lipitor were more likely to be at a greater risk of death when compared to patients who took only statins.
The study was published today in the European Journal of Cardiology.
Rosuvastatin (Crestor) is indicated for the treatment of: 1. In patients with selective heart failure treatment; 2. In patients with left ventricular failure; 3. Right ventricular failure; 4. Homozygous familial premature ventricular atrophy (PPRVA) patients; 5. Patients with glucose-dependent insulinoma (Type 1 diabetes patients); 6. Patients with non-insulinurzyme dependent diabetes (Type 2 diabetes patients); 7. Acute and chronic kidney disease in advanced chronic renal failure (ASC kidney failure); 8. Acute glomerulonecrotic sclerosis (non-severe renal failure); 9. Non-steroidal anti-inflammatory disease (NSAID-positive) patients with moderate to severe inflammation and pain.
Rosuvastatin:Ask your pharmacist or doctor before use in patients with essential hypertension;Treatment:The usual starting dose is one tablet taken at approximately the same time, with or without food. The dose can be increased or decreased depending on response;The adverse events are classified as mild, moderate, and severe.
The recommended dose ofRosuvastatin in patients with essential hypertension is one tablet taken at approximately the same time, with or without food. The dose can be increased or decreased depending on response. The safety of the drug in patients with diabetes, high blood pressure, and renal impairment may be affected. Avoid simultaneous intake of alcohol and grapefruit juice if patients experience decrease in blood pressure. Do not take in combination withRosuvastatin if patients experience mixed effects of essential hypertension and alcohol. If patients experience mixed effects of high blood pressure and alcohol, then consider reduction in the dosage ofRosuvastatin.
Other adverse reactions in patients with essential hypertension may be followed up. Mild adverse effects are usually mild.
The recommended dosage range ofRosuvastatin, as monotherapy or in combination with other anti-hypertensive agents, is one tablet (100 mg) taken at a lower dose of one tablet, with or without food. The safety of the drug in patients with diabetes, high blood pressure, and renal impairment, may be affected. Do not take in combination withRosuvastatin if patients experience decrease in blood pressure. If patients do not experience mixed effects of hypertension and alcohol, then they should decrease the dosage ofRosuvastatin.
May be taken with or without food: Take as-needed: With or Without Needed
Rosuvastatin is contraindicated in patients with hypercholesterolemia (high cholesterol levels) and in patients with coronary heart disease (C-myalgia or anginal skin reaction) and those with severe hepatic impairment. Rosuvastatin should also be avoided in patients with concomitant diseases of the following muscle relaxants and diabetes.
Diabetic patientsDiabetic patients with chronic obstructive pulmonary disease(COPD) and severe hepatic impairment (C-myalgia, anginal skin reaction, exacerbation of emphysema), when the total daily dose of Rosuvastatin (100 mg) is reduced, when the Rosuvastatin dose is increased by 50 mg.
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To treat high cholesterol, Crestor helps reduce the risk of cardiovascular diseases. It lowers the LDL cholesterol and triglycerides in your blood, which are the main bad cholesterol.
Crestor can be taken in two different ways, either with or without food. If you take Crestor with food, you can take it with milk or milk-based milk. If you take Crestor with food, your blood will not be able to clot easily. If you take Crestor with food, the blood clot will also thin your blood.
If you take Crestor with food, you can take Crestor with milk or milk-based milk. You can take Crestor with food in a small amount of time. It is important to follow the dosing instructions carefully and take Crestor regularly.
It is important to take Crestor with food in a small amount of time.
Take Crestor as needed. Swallow Crestor tablets whole and for at least 10-14 days. This can stop the treatment and make the treatment more difficult. It may not work as well if you do not take Crestor with food.
If you take Crestor with food, the blood clot will also also thin your blood.
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